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Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder.

Clinical Studies
Frye, R.E., Melnyk, S., Macfabe, D.F. Transl Psychiatry. 2013; 3:e220. Read Article

A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures.

Clinical Studies
Rossignol, D.A., Frye, R.E. Mol Psychiatry. 2012; 17(4):389-401. Read Article

Substantial problems with measuring brain mitochondrial dysfunction in autism spectrum disorder using magnetic resonance spectroscopy.

Clinical Studies
Rossignol, D.A., Frye, R.E. J Autism Dev Disord. 2012; 42(4):640-2. Read Article

Developmental regression and mitochondrial dysfunction in a child with autism.

Case Studies
Poling, J.S., Frye, R.E., Shoffner, J., Zimmerman, A.W. J Child Neurol. 2006; 21(2):170-2. Read Article

Mitochondrial disease in 22q13 duplication syndrome.

Case Studies
Frye RE. J Child Neurol. 2012; 27(7):942-9. Read Article

Mitochondrial Dysfunction may explain symptom variation in Phelan-McDermid Syndrome.

Case Studies
Frye, R.E., Cox, D., Slattery, J., Tippett, M., Kahler, S., Granpeesheh, D., Damle, S., Legido, A., Goldenthal, M.J. Sci Re...
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The Autism Discovery and Treatment Foundation (ADTF) is a 501c organization dedicated to solving complex medical problems. The overall aim of ADTF is to improve the lives of individuals and families living with chronic diseases which have been difficult to treat and/or cure. Our focus is on autism and other neurodevelopmental disorders.
Info@autismdiscovery.org

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