Blog List

Blog List

Mitochondrial Dysfunction may explain symptom variation in Phelan-McDermid Syndrome.

Case Studies

Frye, R.E., Cox, D., Slattery, J., Tippett, M., Kahler, S., Granpeesheh, D., Damle, S., Legido, A., Goldenthal, M.J. Sci Re...

Autistic Siblings with Novel Mutations in Two Different Genes: Insight for Genetic Workups of Autistic Siblings and Connection to Mitochondrial Dysfunction.

Case Studies

Burger, B.J., Rose, S., Bennuri, S.C., Gill, P.S., Tippett, M.L., Delhey, L., Melnyk, S., Frye, R.E.. Front Pediatr. 2017; ...

Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study.

Cellular Models

Rose, S., Bennuri, S.C., Wynne, R., Melnyk, S., James, S.J., Frye, R.E. FASEB J. 2017; 31(3):904-909. Read Article

Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines.

Cellular Models

Rose, S., Frye, R.E., Slattery, J., Wynne, R., Tippett, M., Melnyk, S., James, S.J. Transl Psychiatry. 2014; 4:e377. Read ...

Oxidative stress induces mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines in a well-matched case control cohort.

Cellular Models

Rose, S., Frye, R.E., Slattery, J., Wynne, R., Tippett, M., Pavliv, O., Melnyk, S., James, S.J. PLoS One. 2014; 9(1):e85436...

Oxidative Stress Challenge Uncovers Trichloroacetaldehyde Hydrate-Induced Mitoplasticity in Autistic and Control Lymphoblastoid Cell Lines.

Toxicants

Frye, R.E., Rose, S., Wynne, R., Bennuri, S.C., Blossom, S., Gilbert, K.M., Heilbrun, L., Palmer, R.F. Sci Rep. 2017; 7(1):...

Increased susceptibility to ethylmercury-induced mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines.

Toxicants

Rose, S., Wynne, R., Frye, R.E., Melnyk, S., James, S.J. J Toxicol. 2015; 2015:573701. Read Article

Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism.

Enteric Short Chain Fatty Acids

Rose, S., Bennuri, S..C, Davis, J.E., Wynne, R., Slattery, J.C., Tippett, M., Delhey, L., Melnyk, S., Kahler, S.G., MacFabe...

The Autism Discovery and Treatment Foundation (ADTF) is a 501c organization dedicated to solving complex medical problems. The overall aim of ADTF is to improve the lives of individuals and families living with chronic diseases which have been difficult to treat and/or cure. Our focus is on autism and other neurodevelopmental disorders.

Info@autismdiscovery.org

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